David William Gregory (15 April 1845 – 4 August 1919) was an Australian cricketer. A right-handed batsman, Gregory was the first Australian national cricket captain, leading the side for the first three recognised Test matches between England and Australia in March and April 1877 and January 1879. Gregory was also the captain of the NSW team, notably during the Sydney Riot of 1879 when he rebelled against an unpopular decision by Victorian umpire George Coulthard during a game against the touring English team.

Gregory was part of a large cricketing family: his father, Edward William Gregory, was a "capable cricketer" with 8 sons, 5 of whom played for NSW in international or intercolonial matches between 1861 and 84; in all, 20 of Edward William Gregory's descendants represented NSW in cricket and other sports.

David William Gregory was a man of striking appearance, he "looked like an Old Testament prophet not long out of training college."